Lysine—pyruvate 6-transaminase

In enzymology, a lysine-pyruvate 6-transaminase (EC 2.6.1.71) is an enzyme that catalyzes the chemical reaction

L-lysine + pyruvate ⇌ L-2-aminoadipate 6-semialdehyde + L-alanine

lysine-pyruvate 6-transaminase
Identifiers
EC no.	2.6.1.71
CAS no.	114189-79-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are L-lysine and pyruvate, whereas its two products are L-2-aminoadipate 6-semialdehyde and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-lysine:pyruvate aminotransferase. Other names in common use include lysine-pyruvate aminotransferase, and Lys-AT.