Michaelis–Becker reaction

The Michaelis–Becker reaction is the reaction of a hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate.^[1] Yields of this reaction are often lower than the corresponding Michaelis–Arbuzov reaction.^[2][3]

Further reading

• Savignac, Philippe; Iorga, Bogdan (2003). Modern phosphonate chemistry. CRC Press. ISBN 978-0-8493-1099-7.