N-acetylneuraminate 4-O-acetyltransferase

In enzymology, a N-acetylneuraminate 4-O-acetyltransferase (EC 2.3.1.44) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + N-acetylneuraminate ${\displaystyle \rightleftharpoons }$ CoA + N-acetyl-4-O-acetylneuraminate

N-acetylneuraminate 4-O-acetyltransferase
Identifiers
EC no.	2.3.1.44
CAS no.	51004-25-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are acetyl-CoA and N-acetylneuraminate, whereas its two products are CoA and N-acetyl-4-O-acetylneuraminate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase. This enzyme is also called sialate O-acetyltransferase.