N6-acetyl-beta-lysine transaminase

In enzymology, a N6-acetyl-beta-lysine transaminase (EC 2.6.1.65) is an enzyme that catalyzes the chemical reaction

6-acetamido-3-aminohexanoate + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ 6-acetamido-3-oxohexanoate + L-glutamate

N6-acetyl-beta-lysine transaminase
Identifiers
EC no.	2.6.1.65
CAS no.	71768-10-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are 6-acetamido-3-aminohexanoate and 2-oxoglutarate, whereas its two products are 6-acetamido-3-oxohexanoate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase. This enzyme is also called epsilon-acetyl-beta-lysine aminotransferase. This enzyme participates in lysine degradation. It employs one cofactor, pyridoxal phosphate.