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Neoflavonoid

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Neoflavonoids are a class of polyphenolic compounds.[1] While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, neoflavonoids have the 4-phenylchromen backbone with no hydroxyl group substitution at position 2.

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Structure of the neoflavonoids backbone (neoflavan represented)

Types

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Chemical structure of 4-phenylcoumarin (neoflavone backbone).

Neoflavonoids include 4-arylcoumarins (neoflavones), 4-arylchromanes, dalbergiones and dalbergiquinols.

  • Neoflavones[1] are derived from the 4-phenylcoumarin (or 4-aryl-coumarin) backbone (C15H12O2).[2] The first neoflavone isolated from natural sources was calophyllolide from Calophyllum inophyllum seeds (1951).[3] It is also found in the bark and timber of the plant Mesua thwaitesii, endemic to Sri Lanka.[4]
  • Neoflavenes possess the 4-phenylchromen backbone (C15H10O2). Dalbergichromene, extracted from the stem-bark and heartwood of Dalbergia sissoo, is an example of such compounds[5]
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Other examples

See also

References

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