P-benzoquinone reductase (NADPH)

In enzymology, a p-benzoquinone reductase (NADPH) (EC 1.6.5.6) is an enzyme that catalyzes the chemical reaction

NADPH + H⁺ + p-benzoquinone ${\displaystyle \rightleftharpoons }$ NADP⁺ + hydroquinone

p-benzoquinone reductase (NADPH)
Identifiers
EC no.	1.6.5.6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The 3 substrates of this enzyme are NADPH, H⁺, and p-benzoquinone, whereas its two products are NADP⁺ and hydroquinone.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is NADPH:p-benzoquinone oxidoreductase. This enzyme participates in gamma-hexachlorocyclohexane degradation.