BRN-3

BRN-3 is a group of related transcription factors in the POU family.^[1] They are also known as class 4 POU domain homeobox proteins.

POU class 4 homeobox 1
Identifiers
Symbol	POU4F1
Alt. symbols	BRN3A
NCBI gene	5457
HGNC	9218
OMIM	601632
RefSeq	NM_006237
UniProt	Q01851
Other data
Locus	Chr. 13 q31.1
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POU class 4 homeobox 2
Identifiers
Symbol	POU4F2
Alt. symbols	BRN3B
NCBI gene	5458
HGNC	9219
OMIM	113725
RefSeq	NM_004575
UniProt	Q12837
Other data
Locus	Chr. 4 q31.22
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POU class 4 homeobox 3
Identifiers
Symbol	POU4F3
Alt. symbols	BRN3C, DFNA15
NCBI gene	5459
HGNC	9220
OMIM	602460
RefSeq	NM_002700
UniProt	Q15319
Other data
Locus	Chr. 5 q32
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There are three BRN-3 proteins encoded by the following genes:

• BRN3A (POU4F1, POU4F1)
• BRN3B (POU4F2, POU4F2)
• BRN3C (POU4F3, POU4F3)

Nomenclature

The BRN or Brn prefix is an abbreviation for "brain"; the longer name is "Brain-specific homeobox". The name of the group may also be abbreviated as POU4, Pou4, POU IV, or POU-IV.