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Pentafluoromethylbenzene
Chemical compound From Wikipedia, the free encyclopedia
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Pentafluoromethylbenzene is a synthetic organofluoride compound with the molecular formula C6F5CH3.[1][2]
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Synthesis
The compound can be obtained by the Friedel–Crafts reaction of pentafluorobenzene with methyl chloride.[3]
Also, the compound can be prepared by reacting hexafluorobenzene with methyllithium.[4][5]
Physical properties
Pentafluoromethylbenzene is a colorless, volatile liquid with a distinctive sweet smell.[5] It is known for its high reactivity, low toxicity, and limited solubility. Additionally, it has the ability to form complexes with metals such as iron and copper.[6]
Chemical properties
The presence of electron-withdrawing fluorine atoms on its aromatic ring significantly enhances the compound reactivity.[6]
Under the influence of light, pentafluoromethylbenzene reacts with bromine to form pentafluorobenzyl bromide.[7]
Uses
This halogenated aromatic hydrocarbon is widely utilized in organic synthesis and analytical chemistry due to its unique characteristics. In scientific studies, the compound is frequently employed to synthesize a variety of organic compounds, including amides, ketones, and carboxylic acids.[6]
See also
References
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