Phosphoribokinase

In enzymology, a phosphoribokinase (EC 2.7.1.18) is an enzyme that catalyzes the chemical reaction

ATP + D-ribose 5-phosphate ${\displaystyle \rightleftharpoons }$ ADP + D-ribose 1,5-bisphosphate

phosphoribokinase
Identifiers
EC no.	2.7.1.18
CAS no.	9030-59-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are ATP and D-ribose 5-phosphate, whereas its two products are ADP and D-ribose 1,5-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-ribose-5-phosphate 1-phosphotransferase. This enzyme is also called phosphoribokinase (phosphorylating).