Phosphoserine

Phosphoserine (abbreviated as SEP or J) is an ester of serine and phosphoric acid. Phosphoserine is a component of many proteins as the result of posttranslational modifications.^[1] The phosphorylation of the alcohol functional group in serine to produce phosphoserine is catalyzed by various types of kinases.^[2][3] Through the use of technologies that utilize an expanded genetic code, phosphoserine can also be incorporated into proteins during translation.^[4][5][6]

l-Phosphoserine

Skeletal formula
Ball-and-stick model
Names
IUPAC name (S)-2-Amino-3-(phosphonooxy)propionic acid
Identifiers
CAS Number	407-41-0 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:15811 Y
ChEMBL	ChEMBL284377 Y
ChemSpider	62074 Y
DrugBank	DB04522 Y
ECHA InfoCard	100.006.352
EC Number	206-986-0
IUPHAR/BPS	1411
KEGG	C01005
MeSH	Phosphoserine
PubChem CID	106
UNII	VI4F0K069V Y
CompTox Dashboard (EPA)	DTXSID1046348
InChI InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1 Y Key: BZQFBWGGLXLEPQ-REOHCLBHSA-N Y InChI=1/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
SMILES O=P(O)(O)OC[C@@H](C(=O)O)N
Properties
Chemical formula	C3H8NO6P
Molar mass	185.073 g/mol
Melting point	228 °C (442 °F; 501 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

It is a normal metabolite found in human biofluids.^[7]

Phosphoserine has three potential coordination sites (carboxyl, amine and phosphate group) Determination of the mode of coordination between phosphorylated ligands and metal ions occurring in an organism is a first step to explain the function of the phosphoserine in bioinorganic processes.^[8][9]