Phylloquinone monooxygenase (2,3-epoxidizing)

In enzymology, a phylloquinone monooxygenase (2,3-epoxidizing) (EC 1.14.99.20) is an enzyme that catalyzes the chemical reaction

phylloquinone + AH₂ + O₂ ${\displaystyle \rightleftharpoons }$ 2,3-epoxyphylloquinone + A + H₂O

phylloquinone monooxygenase (2,3-epoxidizing)
Identifiers
EC no.	1.14.99.20
CAS no.	54596-37-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The three substrates of this enzyme are phylloquinone, an electron acceptor AH₂, and O₂, whereas its three products are 2,3-epoxyphylloquinone, the reduction product A, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O₂ as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing). Other names in common use include phylloquinone epoxidase, vitamin K 2,3-epoxidase, vitamin K epoxidase, and vitamin K₁ epoxidase.