Plasmalogen synthase

In enzymology, a plasmalogen synthase (EC 2.3.1.25) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine ${\displaystyle \rightleftharpoons }$ CoA + plasmenylcholine

plasmalogen synthase
Identifiers
EC no.	2.3.1.25
CAS no.	37257-10-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are acyl-CoA and 1-O-alk-1-enyl-glycero-3-phosphocholine, whereas its two products are CoA and plasmenylcholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase. Other names in common use include lysoplasmenylcholine acyltransferase, O-1-alkenylglycero-3-phosphorylcholine acyltransferase, and 1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase. This enzyme participates in ether lipid metabolism.

See also

• 1-alkenylglycerophosphocholine O-acyltransferase