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T-lymphoblastic leukemia/lymphoma

Medical condition From Wikipedia, the free encyclopedia

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T-lymphoblastic leukemia/lymphoma (WHO 2008),[1]:219 previously labeled precursor T-lymphoblastic leukemia/lymphoma (WHO 2001)[1]:219 is a form of lymphoid leukemia[2][3] and lymphoma[4] in which too many T-cell lymphoblasts (immature white blood cells) are found in the blood, bone marrow, and tissues, particularly mediastinal lymph nodes.[1]:635 Labeling as leukemia or lymphoma depends on which feature is more pronounced in a given situation, but has no biological or treatment implication.[1]:635

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It is uncommon in adults, but represents 15% of childhood acute lymphoblastic leukemia and 90% of lymphoblastic lymphoma.[1]:635

The 2008 terminology dropped "precursor" to avoid linguistic redundancy because the lymphoblast is an immature precursor cell by definition.[1]:219

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