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Promonocyte
Type of cell From Wikipedia, the free encyclopedia
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A promonocyte (or premonocyte) is a cell arising from a monoblast and developing into a monocyte.

Introduction
A promonocyte is an intermediate precursor cell in the monocyte lineage between monoblasts and monocytes, and plays a critical role in immune function and hematopoiesis.
Development and Differentiation
Promonocytes develop from monoblasts in the bone marrow and mature into monocytes, which differentiate into macrophages and dendritic cells.
Morphology
Promonocytes are characterized by distinct cytological features that distinguish them from both monoblasts and mature monocytes.
Immunophenotype
Promonocytes can be identified by their specific surface marker expression via immunophenotyping, which reflects their transitional stage in monocyte development.
Role in Hematopoiesis
Promonocytes are a key transitional cell type ensuring continuous production of monocytes for immune system maintenance.
Clinical Significance
The presence and identification of promonocytes are clinically important in hematological diagnostics and disease classification.
Emerging Diagnostic Approaches
Advances in computational and imaging methods are being developed to improve the recognition of promonocytes.
Research Applications
Promonocytes are studied in immunology and oncology to better understand monocyte development and leukemogenesis.
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See also
Additional images
- Hematopoiesis
- Schematic image of a promonocyte
External links
- "Monocyte Development" at tulane.edu
- Slide at marist.edu
- Histology image: 75_17 at the University of Oklahoma Health Sciences Center - "Bone marrow smear"
- "Maturation Sequence" at hematologyatlas.com (Promonocyte is in seventh row.)
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