Protein-serine epimerase

In enzymology, a protein-serine epimerase (EC 5.1.1.16) is an enzyme that catalyzes the chemical reaction

[protein]-L-serine ${\displaystyle \rightleftharpoons }$ [protein]-D-serine

protein-serine epimerase
Identifiers
EC no.	5.1.1.16
CAS no.	169592-52-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Hence, this enzyme has one substrate, [protein]-L-serine, and one product, [protein]-D-serine.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is [protein]-serine epimerase. This enzyme is also called protein-serine racemase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1WTC.