Pyrazolopyridines

The pyrazolopyridines are a group of drugs investigated as anxiolytics which act as positive allosteric modulators of the GABA_A receptor via the barbiturate binding site.^[1][2] They include the following compounds:

• Cartazolate (SQ-65,396)
• Etazolate (SQ-20,009)
• ICI-190,622
• Tracazolate (ICI-136,753)

Pyrazolo[3,4-b]pyridine, the base chemical structure of this class.

See also

• Barbiturates
• Chlormethiazole
• Etomidate
• Loreclezole