Pyrazolylalanine synthase

The enzyme pyrazolylalanine synthase (EC 4.2.1.50) catalyzes the chemical reaction

L-serine + pyrazole ${\displaystyle \rightleftharpoons }$ 3-(pyrazol-1-yl)-L-alanine + H₂O

pyrazolylalanine synthase
Identifiers
EC no.	4.2.1.50
CAS no.	37290-81-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is L-serine hydro-lyase [adding pyrazole 3-(pyrazol-1-yl)-L-alanine-forming]. Other names in common use include β-pyrazolylalaninase, β-(1-pyrazolyl)alanine synthase, and L-serine hydro-lyase (adding pyrazole). It employs one cofactor, pyridoxal phosphate.