Pyridine-3-carbaldehyde

Pyridine-3-carbaldehyde, also known as nicotinaldehyde, is an organic compound with the formula C₅H₄NCHO. It is one of three isomeric pyridinaldehydes. The other isomers are pyridine-2-carboxaldehyde and pyridine-4-carboxaldehyde. It is a colorless liquid that is routinely available commercially. It can be produced from nicotinonitrile. Alternatively, it arises by the aerobic oxidation of the corresponding alcohol.^[1]

Pyridine-3-carbaldehyde

Names
Preferred IUPAC name Pyridine-3-carbaldehyde
Other names Nicotinaldehyde, 3-formylpyridine, 3-pyridinaldehyde
Identifiers
CAS Number	500-22-1
3D model (JSmol)	Interactive image
ChEBI	CHEBI:28345
ChEMBL	ChEMBL268493
ChemSpider	9943
ECHA InfoCard	100.007.183
EC Number	207-900-4
KEGG	C07327
PubChem CID	10371
UNII	840R4IDQ1T
CompTox Dashboard (EPA)	DTXSID2022044
InChI InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H Key: QJZUKDFHGGYHMC-UHFFFAOYSA-N
SMILES C1=CC(=CN=C1)C=O
Properties
Chemical formula	C6H5NO
Molar mass	107.112 g·mol−1
Appearance	colorless liquid
Density	1.14 g/cm3
Melting point	7 °C (45 °F; 280 K)
Boiling point	95–97 °C (203–207 °F; 368–370 K) 15 mm
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H226, H302, H315, H317, H318, H334, H335, H341, H412
Precautionary statements	P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P272, P273, P280, P281, P285, P301+P312, P302+P352, P303+P361+P353, P304+P340, P304+P341, P305+P351+P338, P308+P313, P310, P312, P321, P330, P332+P313, P333+P313, P342+P311, P362, P363, P370+P378, P403+P233, P403+P235, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Safety

3-Pyridinecarboxaldehyde is a severe skin irritant.^[2]