Pyridoxamine—pyruvate transaminase

In enzymology, a pyridoxamine-pyruvate transaminase (EC 2.6.1.30) is an enzyme that catalyzes the chemical reaction:

pyridoxamine + pyruvate ${\displaystyle \rightleftharpoons }$ pyridoxal + L-alanine

pyridoxamine-pyruvate transaminase
Identifiers
EC no.	2.6.1.30
CAS no.	9023-38-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are pyridoxamine and pyruvate, whereas its two products are pyridoxal and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is pyridoxamine:pyruvate aminotransferase. This enzyme is also called pyridoxamine-pyruvic transaminase. This enzyme participates in vitamin B₆ metabolism.