Tulane virus

Tulane virus (Recovirus tulani) is a calicivirus isolated from the rhesus monkey.^[2] It is the sole member of the Recovirus genus.^[3] It is a non-enveloped, positive-sense, single-stranded RNA virus, and its genome, which is approximately 6.7 kilobases in length, is reported shortest among the members of the family Caliciviridae . The genome is organized into three open reading frames (ORFs): ORF1 encodes a nonstructural polyprotein involved in viral replication, ORF2 endcodes the major capsid protein (VP1), and ORF3 encodes a basic minor structural protein (VP2)^[4].

Tulane virus
Virus classification
(unranked):	Virus
Realm:	Riboviria
Kingdom:	Orthornavirae
Phylum:	Pisuviricota
Class:	Pisoniviricetes
Order:	Picornavirales
Family:	Caliciviridae
Genus:	Recovirus
Species:	Recovirus tulani
Synonyms[1]
Recovirus A

The virus was first identified in 2008 after being isolated from the stool samples of captive juvenile rhesus macaques (Macaca mulatta) housed at the Tulane National Primate Research Center^[4]. It propagates easily in cell lines such as LLC-MK2^[5], and recognizes histo-blood group antigens (HBGAs) similar to human noroviruses (HuNoVs)^[6]. These features make it a good surrogate candidate for HuNoV studies.