(Fructose-bisphosphate aldolase)-lysine N-methyltransferase

The correct title of this article is [Fructose-bisphosphate aldolase]-lysine N-methyltransferase. It appears incorrectly here due to technical restrictions.

[Fructose-bisphosphate aldolase]-lysine N-methyltransferase (EC 2.1.1.259)^[1][2] is an enzyme that catalyses the following chemical reaction:

3 S-adenosyl-L-methionine + [fructose-bisphosphate aldolase]-L-lysine ${\displaystyle \rightleftharpoons }$ 3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N⁶,N⁶,N⁶-trimethyl-L-lysine

(Fructose-bisphosphate aldolase)-lysine N-methyltransferase
Identifiers
EC no.	2.1.1.259
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC 4.1.2.13).

Nomenclature

The systematic name of the enzyme is:

• S-adenosyl-L-methionine:(fructose-bisphosphate aldolase)-lysine N⁶-methyltransferase

Other names are:

• rubisco methyltransferase
• ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase
• ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase
• S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase)^[2]

See also

• Methyllysine
• RuBisCO
• SET domain