SB-243213

SB-243213 is a research chemical which acts as a selective inverse agonist for the 5HT_2C receptor and has anxiolytic effects. It has better than 100x selectivity for 5-HT_2C over all other receptor subtypes tested, and a longer duration of action compared to older 5-HT_2C antagonist ligands.^{[1][2][3][4][5][6][7][8]}

SB-243213

Identifiers
IUPAC name 5-methyl-N-(6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl)-6-(trifluoromethyl)indoline-1-carboxamide
CAS Number	200940-23-4
PubChem CID	443391
ChemSpider	391620
UNII	PA86JD65ZJ
CompTox Dashboard (EPA)	DTXSID0047323
Chemical and physical data
Formula	C22H19F3N4O2
Molar mass	428.415 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C(C(F)(F)F)C=C(N(C(NC2=CN=C(OC3=C(C)N=CC=C3)C=C2)=O)CC4)C4=C1
InChI InChI=1S/C22H19F3N4O2/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30) Key:ZETBBVYSBABLHL-UHFFFAOYSA-N

See also

• CEPC
• RS-102221
• SB-242084