Speeter–Anthony route

The Speeter–Anthony route, also known as the Speeter–Anthony tryptamine synthesis (STS), is a well-known and widely used chemical synthesis route used in the synthesis of tryptamines, including psychedelic tryptamines like psilocin and 5-MeO-DiPT.^[1][2][3] It starts with indole or a ring-substituted indole.^[1][2] The scheme of the route is as follows:^[2]

Other tryptamine synthesis routes have also been described, for instance starting with tryptamine rather than indole.^[1][2]