Sphinganine-1-phosphate aldolase

The enzyme sphinganine-1-phosphate aldolase (EC 4.1.2.27) catalyzes the chemical reaction

sphinganine 1-phosphate ${\displaystyle \rightleftharpoons }$ phosphoethanolamine + palmitaldehyde

sphinganine-1-phosphate aldolase
Identifiers
EC no.	4.1.2.27
CAS no.	39391-27-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming). Other names in common use include dihydrosphingosine 1-phosphate aldolase, sphinganine-1-phosphate alkanal-lyase, sphinganine-1-phosphate lyase, and sphinganine-1-phosphate palmitaldehyde-lyase. This enzyme participates in sphingolipid metabolism. It employs one cofactor, pyridoxal phosphate.