Suriclone

Suriclone (Suril) is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. Other cyclopyrrolone drugs include zopiclone and pagoclone.

Suriclone

Clinical data
ATC code	none
Identifiers
IUPAC name [6-(7-chloro-1,8-naphthyridin-2-yl)-5-oxo-3,7-dihydro-2H-[1,4]dithiino[2,3-c]pyrrol-7-yl] 4-methylpiperazine-1-carboxylate
CAS Number	53813-83-5 N
PubChem CID	40903
ChemSpider	37353 Y
UNII	LNC9G689VR
ChEMBL	ChEMBL2105561 N
CompTox Dashboard (EPA)	DTXSID20866362
ECHA InfoCard	100.053.431
Chemical and physical data
Formula	C20H20ClN5O3S2
Molar mass	477.98 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc4nc5nc(N3C(=O)C=1SCCSC=1C3OC(=O)N2CCN(C)CC2)ccc5cc4
InChI InChI=1S/C20H20ClN5O3S2/c1-24-6-8-25(9-7-24)20(28)29-19-16-15(30-10-11-31-16)18(27)26(19)14-5-3-12-2-4-13(21)22-17(12)23-14/h2-5,19H,6-11H2,1H3 Y Key:RMXOUBDDDQUBKD-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Suriclone has a very similar pharmacological profile to the benzodiazepine family of drugs including sedative and anxiolytic properties but with less amnestic effects,^[1][2] and its chemical structure is quite different from that of the benzodiazepine drugs.

The mechanism of action by which suriclone produces its sedative and anxiolytic effects is by modulating GABA_A receptors, although suriclone is more subtype-selective than most benzodiazepines.^[3]