Sym-norspermidine synthase

In enzymology, a sym-norspermidine synthase (EC 2.5.1.23) is an enzyme that catalyzes the chemical reaction

S-adenosylmethioninamine + propane-1,3-diamine ${\displaystyle \rightleftharpoons }$ 5'-methylthioadenosine + bis(3-aminopropyl)amine

sym-norspermidine synthase
Identifiers
EC no.	2.5.1.23
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are S-adenosylmethioninamine and propane-1,3-diamine, whereas its two products are 5'-methylthioadenosine and bis(3-aminopropyl)amine.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase. This enzyme participates in urea cycle and metabolism of amino groups.