Tartrate dehydrogenase

In enzymology, a tartrate dehydrogenase (EC 1.1.1.93) is an enzyme that catalyzes the chemical reaction

tartrate + NAD⁺ ${\displaystyle \rightleftharpoons }$ oxaloglycolate + NADH + H⁺

tartrate dehydrogenase
Tartrate dehydrogenase tetramer, Pseudomonas putida
Identifiers
EC no.	1.1.1.93
CAS no.	37250-29-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are tartrate and NAD⁺, whereas its 3 products are oxaloglycolate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is tartrate:NAD⁺ oxidoreductase. This enzyme is also called mesotartrate dehydrogenase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, manganese.