Taurine—pyruvate aminotransferase

In enzymology, a taurine-pyruvate aminotransferase (EC 2.6.1.77) is an enzyme that catalyzes the chemical reaction.

taurine + pyruvate ${\displaystyle \rightleftharpoons }$ L-alanine + 2-sulfoacetaldehyde

taurine-pyruvate aminotransferase
Identifiers
EC no.	2.6.1.77
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are taurine and pyruvate, whereas its two products are L-alanine and 2-sulfoacetaldehyde.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is taurine:pyruvate aminotransferase. This enzyme is also called Tpa. This enzyme participates in taurine and hypotaurine metabolism.