Thioether S-methyltransferase

In enzymology, a thioether S-methyltransferase (EC 2.1.1.96) is an enzyme that catalyzes the chemical reaction.

S-adenosyl-L-methionine + dimethyl sulfide ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + trimethylsulfonium

thioether S-methyltransferase
Identifiers
EC no.	2.1.1.96
CAS no.	114797-02-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are S-adenosyl methionine and dimethyl sulfide, whereas its two products are S-adenosylhomocysteine and trimethylsulfonium.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase. Other names in common use include S-adenosyl-L-methionine:thioether S-methyltransferase, and thioether methyltransferase.