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Thymidylate 5'-phosphatase

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The enzyme thymidylate 5′-phosphatase (EC 3.1.3.35) catalyzes the reaction

thymidylate + H2O thymidine + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is thymidylate 5′-phosphohydrolase. Other names in common use include thymidylate 5′-nucleotidase, deoxythymidylate 5′-nucleotidase, thymidylate nucleotidase, deoxythymidylic 5′-nucleotidase, deoxythymidylate phosphohydrolase, and dTMPase.

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