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Translational Health Science and Technology Institute

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The Translational Health Science and Technology Institute (THSTI), an institute of Biotechnology Research and Innovation Council (BRIC), Department of Biotechnology, Ministry of Science and Technology, Government of India, is dedicated to translating fundamental scientific discoveries into tangible healthcare solutions. Prof Ganesan Karthikeyan is the current executive director of THSTI.

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Established in 2009 in the NCR Biotech Science Cluster, Faridabad, THSTI plays a crucial role in India's efforts to advance public health through translational research. THSTI's research focus includes vaccines, therapeutics such as monoclonal antibodies, microbial consortia, immunotherapy and immunobiology, maternal and child health, diagnostics, and Non-alcoholic fatty liver disease. The institute has state-of-the-art facilities such as Bioassay Laboratory (ISO 17025:2017), Biorepository (ISO 20387:2018), Biosafety Level-3 Lab, Experimental Animal Facility, Multi-OMICS facility, etc. THSTI’s upcoming Medical Research Centre (MRC) will be a 50-bed facility that will serve as a pivotal hub for accelerating the translation of scientific discoveries into impactful healthcare solutions, with a strong emphasis on early clinical trials and precision therapies such as CAR-T. MRC also houses the first Centre for Controlled Human Infection Studies in India and South Asia. The centre will also house a dedicated DMPK (Drug Metabolism and Pharmacokinetics) unit for understanding how drugs are absorbed, distributed, metabolized, and eliminated by the body, enabling researchers to optimize drug candidates for maximum efficacy and safety. Complementing the MRC, the Translational Research Facility (TRF) is designed to streamline the entire medical product development pipeline, from bench to biomanufacturing (pilot scale). The TRF will provide critical support for the development of vaccines, monoclonal antibodies, diagnostics, and biotherapeutics. It is envisioned to host multiple Centres of Excellence, fostering collaborations with both industry and academia to drive innovation and accelerate the commercialisation of healthcare solutions.


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Scientists at THSTI

Executive Director

  • Prof. Ganesan Karthikeyan

References

{https://thsti.res.in/}


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