Trifluoromethoxy group

The trifluoromethoxy group is the chemical group –O–CF
₃. It can be seen as a methoxy group –O–CH
₃ whose hydrogen atoms are replaced by fluorine atoms; or as a trifluoromethyl group attached to the rest of the molecule by a bridging oxygen atom; either leads to viable syntheses.^[1] Compounds having this functional group are of some relevance as pharmaceuticals. One example is riluzole.