Lamivudine/nevirapine/stavudine

Lamivudine/nevirapine/stavudine (3TC/NVP/d4T) is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS.^[1] It contains lamivudine, nevirapine, and stavudine.^[1] It is either used by itself or along with other antiretrovirals.^[1] It is taken by mouth twice a day.^[1]

Lamivudine/nevirapine/stavudine

Combination of
Lamivudine	nucleoside reverse transcriptase inhibitor
Nevirapine	non-nucleoside reverse transcriptase inhibitor
Stavudine	nucleoside reverse transcriptase inhibitor
Clinical data
Trade names	Triomune, others
ATC code	J05AR07 (WHO)
Identifiers
CAS Number	811471-91-7
ChemSpider	none

It is on the World Health Organization's List of Essential Medicines.^[2] As of 2015, it is not commercially available in the United States.^[3]

Medical uses

It is a common first line treatment in the developing world.^[4]

Adverse effects and safety

The medication is generally well tolerated.^[5] Side effects are those of the underlying medications.^[1] This may include rash, numbness, pancreatitis, and high blood lactate levels.^[5] Use is not recommended in those with significant liver problems.^[5] It is unclear if use in pregnancy is safe for the baby and recommendations include starting in the second trimester if possible.^[5]