Triphosphoribosyl-dephospho-CoA synthase

In enzymology, a triphosphoribosyl-dephospho-CoA synthase (EC 2.7.8.25) is an enzyme that catalyzes the chemical reaction

ATP + 3-dephospho-CoA ${\displaystyle \rightleftharpoons }$ 2'-(5"-triphosphoribosyl)-3'-dephospho-CoA + adenine

triphosphoribosyl-dephospho-CoA synthase
Identifiers
EC no.	2.7.8.25
CAS no.	313345-38-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are ATP and 3-dephospho-CoA, whereas its two products are 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA and adenine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is ATP:3-dephospho-CoA 5"-triphosphoribosyltransferase. Other names in common use include 2'-(5"-triphosphoribosyl)-3-dephospho-CoA synthase, ATP:dephospho-CoA 5-triphosphoribosyl transferase, and CitG. This enzyme participates in two-component system - general.