UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase

In enzymology, an UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase (EC 2.7.8.18) is an enzyme that catalyzes the chemical reaction

UDP-galactose + UDP-N-acetyl-D-glucosamine ${\displaystyle \rightleftharpoons }$ UMP + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine

UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase
Identifiers
EC no.	2.7.8.18
CAS no.	84932-43-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are UDP-galactose and UDP-N-acetyl-D-glucosamine, whereas its two products are UMP and UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups transferases for other substituted phosphate groups. The systematic name of this enzyme class is UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase. Other names in common use include uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase, galactose-1-phosphotransferase, and galactosyl phosphotransferase.