Tooth and nail syndrome

Tooth and nail syndrome (also known as hypodontia with nail dysgenesis, Witkop syndrome, or mucoepithelial dysplasia syndrome)^{[1][2][page needed]} is a rare disorder, first described in 1965, characterized by nails that are thin, small, and friable, and which may show koilonychia at birth.^{[2]: 521 [3]} It was named after Dr. Carl J. Witkop Jr., who first described it between 1978 and 1982.^[1] It is an autosomal dominant type of ectodermal dysplasia.^[4] Its estimated incidence is 2 in 10,000.^[4]

Tooth and nail syndrome
This condition is inherited in an autosomal dominant manner.
Specialty	Medical genetics

It is associated with MSX1.^[5]

See also

• Skin lesion
• List of cutaneous conditions