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XK (protein)
Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
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XK (also known as Kell blood group precursor) is a protein found on human red blood cells and other tissues which is responsible for the Kx antigen which helps determine a person's blood type.
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Clinical significance
The Kx antigen plays a role in matching blood for blood transfusions.[citation needed]
Mutation of XK protein may lead to McLeod syndrome,[1] a multi-system disorder characterized by hemolytic anemia, myopathy, acanthocytosis, and chorea.[2]
XK is located on the X chromosome (cytogenetic band Xp21.1) and absence of the XK protein is an X-linked disease.[3]
Function
XK is a membrane transport protein of unknown action.[4]
References
External links
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