Z-farnesyl diphosphate synthase

In enzymology, a Z-farnesyl diphosphate synthase (EC 2.5.1.68) is an enzyme that catalyzes the chemical reaction

geranyl diphosphate + isopentenyl diphosphate ${\displaystyle \rightleftharpoons }$ diphosphate + (2Z,6E)-farnesyl diphosphate

Z-farnesyl diphosphate synthase
Identifiers
EC no.	2.5.1.68
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are geranyl diphosphate and isopentenyl diphosphate, whereas its two products are diphosphate and (2Z,6E)-farnesyl diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase. This enzyme is also called (Z)-farnesyl diphosphate synthase.