See also: esc, ESC, -esc, and ␛ English Noun Esc Abbreviation of escape key (on a computer keyboard). Synonym: Esc key Anagrams ces, CSE, ECS, sec., S. E. C., S.E.C., SEC, SCE, sec, CEs, sce., sec-, CES, Sec.Wikiwand - on Seamless Wikipedia browsing. On steroids.Remove ads