synaptotoxicity

English

Etymology

From synapto- +‎ toxicity.

Noun

synaptotoxicity (countable and uncountable, plural synaptotoxicities)

1. The condition of being synaptotoxic
   • 2015 November 6, “The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy”, in PLOS ONE‎, →DOI:

     Compared with vehicle-treated controls, rapamycin protected against the tau-induced neuronal loss, synaptotoxicity, reactive microgliosis and astrogliosis, and activation of innate neuroimmunity.