Enteric coating
Coating added to some oral medications / From Wikipedia, the free encyclopedia
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An enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment.[1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine).[2] Some drugs are unstable at the pH of gastric acid and need to be protected from degradation. Enteric coating is also an effective method to obtain drug targeting (such as gastro-resistant drugs). Other drugs such as some anthelmintics may need to reach a high concentration in a specific part of the intestine.[1] Enteric coating may also be used during studies as a research tool to determine drug absorption.[3] Enteric-coated medications pertain to the "delayed action" dosage form category. Tablets, mini-tablets, pellets and granules (usually filled into capsule shells) are the most common enteric-coated dosage forms.[3]