Glycophorin
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A glycophorin is a sialoglycoprotein of the membrane of a red blood cell. It is a membrane-spanning protein and carries sugar molecules. It is heavily glycosylated (60%). Glycophorins are rich in sialic acid, which gives the red blood cells a very hydrophilic-charged coat. This enables them to circulate without adhering to other cells or vessel walls.
Quick Facts Identifiers, Symbol ...
Glycophorin A | |||||||||
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Identifiers | |||||||||
Symbol | GYPA | ||||||||
Pfam | PF01102 | ||||||||
InterPro | IPR001195 | ||||||||
PROSITE | PDOC00281 | ||||||||
SCOP2 | 1afo / SCOPe / SUPFAM | ||||||||
OPM superfamily | 25 | ||||||||
OPM protein | 5eh4 | ||||||||
Membranome | 156 | ||||||||
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A particular mutation in Glycophorins is thought to produce a 40% reduction in risk of severe malaria. [1]