Lipoxin
Acronym for lipoxygenase interaction product / From Wikipedia, the free encyclopedia
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A lipoxin (LX or Lx), an acronym for lipoxygenase interaction product, is a bioactive autacoid metabolite of arachidonic acid made by various cell types. They are categorized as nonclassic eicosanoids and members of the specialized pro-resolving mediators (SPMs) family of polyunsaturated fatty acid (PUFA) metabolites. Like other SPMs, LXs form during, and then act to resolve, inflammatory responses. Initially, two lipoxins were identified, lipoxin A4 (LXA4) and LXB4, but more recent studies have identified epimers of these two LXs: the epi-lipoxins, 15-epi-LXA4 and 15-epi-LXB4 respectively.
Quick Facts Names, Identifiers ...
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Preferred IUPAC name
(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxyicosa-6,8,10,12-tetraenoic acid | |
Other names
LXB4 | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChemSpider |
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PubChem CID |
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Properties | |
C20H32O5 | |
Molar mass | 352.46508 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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