The 2018 Open 13 Provence was a men's tennis tournament played on indoor hard courts. It was the 25th edition of the Open 13, and part of the ATP World Tour 250 series of the 2018 ATP World Tour. It took at the Palais des Sports in Marseille, France, from 19 February through 25 February 2018. Ninth-seeded Karen Khachanov won the singles title.