The 2022 James Madison Dukes football team represented James Madison University in the 2022 NCAA Division I FBS football season. They were led by fourth-year head coach Curt Cignetti. The Dukes played their home games at Bridgeforth Stadium in Harrisonburg, Virginia as members of the East division of the Sun Belt Conference. The Dukes finished the season 8–3, 6–2 in Sun Belt play to finish in a tie for first place in the East division.