Bethlehem Union Station is a former train station located in the South Side neighborhood of Bethlehem, Pennsylvania. It was built in 1924 by the Lehigh Valley Railroad and the Reading Company, replacing an earlier station built in 1867. Passenger service to Philadelphia on the SEPTA Regional Rail Bethlehem Line lasted until 1981. The station was renovated in 2002 and used for medical clinics beginning in 2003. It is owned by St. Luke's Hospital.