Colnbrook is a village in the Slough district in Berkshire, England. It lies within the historic boundaries of Buckinghamshire, and straddles two distributaries of the Colne, the Colne Brook and Wraysbury River. These two streams have their confluence just to the southeast of the village. Colnbrook is centred 3 miles (4.8 km) southeast of the Slough town centre, 4 miles (6.4 km) east of Windsor, and 19 miles (31 km) west of central London.