Compton Chamberlayne is a small village and civil parish in the Nadder Valley in south Wiltshire, England, about 7 miles (11 km) west of Salisbury. The Nadder forms the northern boundary of the parish; to the south are chalk hills. It is bisected by the A30 road. The village contains some 25 privately owned houses, a village hall, and a cricket pitch used by Compton Chamberlayne Cricket Club.