Cyrildene is a suburb of Johannesburg, South Africa, predominantly home to Chinese people. The area is found east of the Johannesburg CBD and is surrounded by the suburbs of Linksfield, Observatory and Bruma. It is noted for a new Chinatown that exists on Derrick Avenue. This new Chinatown is now considered as the main Chinatown in Johannesburg, replacing the declining Chinatown on Commissioner Street in the inner-city of Johannesburg. It is located in Region F of the City of Johannesburg Metropolitan Municipality.