The John Rylands Research Institute and Library is a late-Victorian neo-Gothic building on Deansgate in Manchester, England. It is part of the University of Manchester. The library, which opened to the public in 1900, was founded by Enriqueta Augustina Rylands in memory of her husband, John Rylands. It became part of the university in 1972, and now houses the majority of the Special Collections of The University of Manchester Library, the third largest academic library in the United Kingdom.